SCHEMBL31125352

SCHEMBL31125352

C#CCOc1cccc(-c2ccc(NC(=O)C3=C(C(=O)O)CCC3)c(F)c2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 20/20 1.00
NR4A2 P43354 7/20 1.00
NR4A1 P22736 2/20 1.00
JMJD7 P0C870 1/20 0.72
NR4A3 Q92570 1/20 0.72
NR1H4 Q96RI1 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31125350 0.91 DHODH (0.84) DHODHNR4A2NR4A1JMJD7NR4A3
SCHEMBL254247 0.87 DHODH (0.84) DHODHNR4A2NR4A1JMJD7NR4A3
Vidofludimus SCHEMBL29352865 0.84 DHODH (1.00) DHODHNR4A2NR4A1JMJD7NR4A3
Vidofludimus SCHEMBL247888 0.84 DHODH (1.00) DHODHNR4A2NR4A1JMJD7NR4A3
Vidofludimus SCHEMBL28974266 0.83 DHODH (0.98) DHODHNR4A2NR4A1JMJD7NR4A3
SCHEMBL3917145 0.82 DHODH (1.00) DHODHNR4A2NR4A1JMJD7NR4A3
SCHEMBL29869086 0.81 DHODH (0.80) DHODHNR4A2NR4A1JMJD7NR4A3
Vidofludimus SCHEMBL29869156 0.81 DHODH (1.00) DHODHNR4A2NR4A1JMJD7NR4A3
SCHEMBL18118644 0.81 DHODH (0.83) DHODHNR4A2NR4A1JMJD7NR4A3
SCHEMBL4398584 0.81 DHODH (0.75) DHODHNR4A2NR4A1JMJD7NR4A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260130879-A1 VIDOFLUDIMUS AND RELATED STRUCTURES ACTING AS NURR1 AGONISTS IMMUNIC AG (DE) 2026-05-14 US disclosed
EP-4687869-A1 VIDOFLUDIMUS AND RELATED STRUCTURES ACTING AS NURR1 AGONISTS Immunic AG (DE) 2026-02-11 EP disclosed
US-20240335405-A1 VIDOFLUDIMUS AND RELATED STRUCTURES ACTING AS NURR1 AGONISTS IMMUNIC AG (DE) 2024-10-10 US disclosed
WO-2024200872-A1 VIDOFLUDIMUS AND RELATED STRUCTURES ACTING AS NURR1 AGONISTS IMMUNIC AG (DE) 2024-10-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260130879-A1 VIDOFLUDIMUS AND RELATED STRUCTURES ACTING AS NURR1 AGONISTS NR0B1, NR4A1, NR4A2 DHODH 15/4885NR4A2 3/4885NR4A1 2/4885
US-20240335405-A1 VIDOFLUDIMUS AND RELATED STRUCTURES ACTING AS NURR1 AGONISTS NR4A1, NR4A2, NR0B1 DHODH 2057/4885NR4A2 2/4885NR4A1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.