Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.31 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | F13A1 | P00488 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
| ▸ | TGM1 | P22735 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31125399 | 0.83 | — | — | |
| SCHEMBL31125471 | 0.79 | ATM (0.35) | HSD11B1CHRM2CHRM1CHRM3DDB1 | |
| SCHEMBL31125458 | 0.78 | MAPK1 (0.35) | MAPK1HSD11B1CHRM2CHRM1CHRM3 | |
| SCHEMBL20484736 | 0.78 | NR1H2 (0.40) | DDB1CRBNCCNE1CDK2GSK3B | |
| SCHEMBL31125452 | 0.78 | NPC1 (0.41) | MAPK1NR1H2NPC1 | |
| SCHEMBL31125513 | 0.77 | CCNE1 (0.34) | CCNE1CDK2GSK3BNR1H2 | |
| SCHEMBL31125625 | 0.77 | NPC1 (0.41) | HSD11B1NPC1 | |
| SCHEMBL15591345 | 0.75 | CCNE1 (0.34) | CCNE1CDK2GSK3B | |
| SCHEMBL372025 | 0.75 | ELANE (0.34) | MAPK1CHRM2CHRM1CHRM3POLB | |
| SCHEMBL28672971 | 0.74 | EPHX1 (0.43) | MAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113195053-B | Amino acid compounds and methods of use | 普利安特治疗公司 | 2024-08-30 | — | — | CN | disclosed |