SCHEMBL31126751

SCHEMBL31126751

CN1C[C@@H](CC(C)(C)N)CCC1=O

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 4/20 0.41
SRD5A1 P18405 4/20 0.39
SRD5A2 P31213 2/20 0.33
BRD2 P25440 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31312201 0.78 BRD4 (0.46) BRD4SRD5A1SRD5A2BRD2
SCHEMBL26788780 0.76 BRD4 (0.47) BRD4SRD5A1SRD5A2BRD2
SCHEMBL23107033 0.76 BRD4 (0.47) BRD4SRD5A1SRD5A2BRD2
SCHEMBL21859839 0.76 BRD4 (0.47) BRD4SRD5A1SRD5A2BRD2
SCHEMBL31027444 0.74 BRD4 (0.66) BRD4SRD5A1SRD5A2BRD2
SCHEMBL21475939 0.73 BRD4 (0.46) BRD4SRD5A1SRD5A2BRD2
SCHEMBL31126694 0.72 BRD4 (0.41) BRD4BRD2
SCHEMBL19296766 0.71 BRD4 (0.43) BRD4SRD5A1SRD5A2BRD2
SCHEMBL27758738 0.71 BRD4 (0.40) BRD4SRD5A1SRD5A2BRD2
SCHEMBL27737854 0.71 BRD4 (0.40) BRD4SRD5A1SRD5A2BRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4688738-A1 HETEROCYCLOALKYL BETA-HYDROXY ALKYL AMINES FOR USE IN THE TREATMENT OF HYPERGLYCAEMIA AND DISORDERS CHARACTERISED BY HYPERGLYCAEMIA Atrogi AB (SE) 2026-02-11 EP disclosed
WO-2024200736-A1 HETEROCYCLOALKYL BETA-HYDROXY ALKYL AMINES FOR USE IN THE TREATMENT OF HYPERGLYCAEMIA AND DISORDERS CHARACTERISED BY HYPERGLYCAEMIA ATROGI AB (SE) 2024-10-03 WO disclosed