Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5179200 | 0.88 | TSHR (0.45) | TSHRGLAPOLBGAACYP3A4 | |
| SCHEMBL1040870 | 0.88 | TSHR (0.45) | TSHRGLAPOLBGAACYP3A4 | |
| SCHEMBL25077717 | 0.84 | GAA (0.42) | TSHRGLAPOLBGAACYP3A4 | |
| SCHEMBL12397904 | 0.84 | GAA (0.42) | TSHRGLAPOLBGAACYP3A4 | |
| SCHEMBL15556074 | 0.80 | TSHR (0.42) | TSHRGLAPOLBGAACYP3A4 | |
| SCHEMBL3115697 | 0.79 | GAA (0.50) | TSHRGLAPOLBGAAALDH1A1 | |
| SCHEMBL2434618 | 0.78 | CYP3A4 (0.56) | TSHRGLAPOLBGAACYP3A4 | |
| SCHEMBL20045608 | 0.78 | CYP3A4 (0.46) | TSHRGLAPOLBGAACYP3A4 | |
| SCHEMBL30739915 | 0.78 | CYP3A4 (0.46) | TSHRGLAPOLBGAACYP3A4 | |
| SCHEMBL11844970 | 0.78 | GAA (0.54) | TSHRGLAPOLBGAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100179172-A1 | N-PHENYL-METHANAMINE DERIVATIVE AND PESTICIDE CONTAINING IT | ISHIHARA SANGYO KAISHA , LTD. (JP) | 2010-07-15 | — | — | US | disclosed |
| EP-2172456-A1 | N-PHENYL-METHANAMINE DERIVATIVE AND PEST CONTROL AGENT CONTAINING THE SAME | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179172-A1 | N-PHENYL-METHANAMINE DERIVATIVE AND PESTICIDE CONTAINING IT | CHRM2, CHRM5, CHRM3 | TSHR 454/4885GLA 4728/4885POLB 3136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.