Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 2/20 | 0.45 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PRNP | P04156 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31128305 | 0.93 | PSMB5 (0.37) | PSMB5NQO2LMNAPRNPHPGD | |
| SCHEMBL31128380 | 0.82 | PSMB5 (0.47) | PSMB5PDE10ASCN10A | |
| SCHEMBL31128208 | 0.79 | PSMB5 (0.45) | PSMB5KDM4EMEN1MAPTKMT2A | |
| SCHEMBL31128334 | 0.74 | PSMB5 (0.39) | PSMB5LMNAHPGD | |
| SCHEMBL31128288 | 0.71 | PSMB5 (0.37) | PSMB5KMT2ALMNAHTTPIK3CA | |
| SCHEMBL1201473 | 0.71 | NQO2 (0.48) | NQO2KDM4EMAPTLMNAPRNP | |
| SCHEMBL30186062 | 0.69 | NQO2 (0.42) | NQO2KDM4EMAPTLMNAPRNP | |
| SCHEMBL15195556 | 0.69 | NQO2 (0.42) | NQO2KDM4EMAPTLMNAPRNP | |
| SCHEMBL16905120 | 0.68 | KDM4E (0.35) | PSMB5KDM4EMEN1MAPTKMT2A | |
| SCHEMBL31128303 | 0.66 | NQO2 (0.39) | NQO2LMNAPRNPHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024166131-A1 | HETEROARYL COMPOUNDS AS PKMYT1 INHIBITORS | SATYARX PHARMA INNOVATIONS PRIVATE LIMITED (IN) | 2024-08-15 | — | — | WO | disclosed |