Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31128966 | 0.91 | CYP3A4 (0.41) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL31128969 | 0.90 | FGFR1 (0.48) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL31128874 | 0.87 | KDR (0.42) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL31128990 | 0.84 | FGFR1 (0.50) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL31128994 | 0.83 | FGFR1 (0.41) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL31128959 | 0.81 | FGFR1 (0.62) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL31128884 | 0.80 | FGFR1 (0.40) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL31129020 | 0.80 | CYP3A4 (0.41) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL31128829 | 0.79 | CYP3A4 (0.46) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL31128839 | 0.78 | FGFR1 (0.46) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024208315-A1 | AROMATIC HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 中国医药研究开发中心有限公司 | 2024-10-10 | — | — | WO | disclosed |