Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 15/20 | 0.46 |
| ▸ | FEN1 | P39748 | 14/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31128809 | 0.86 | ALOX5AP (0.35) | ALOX5APFEN1EPHB4 | |
| SCHEMBL31128954 | 0.83 | EPHB4 (0.56) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL31128936 | 0.81 | ALOX5AP (0.39) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL31128959 | 0.79 | FGFR1 (0.62) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL31129032 | 0.77 | CYP3A4 (0.41) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL31129030 | 0.76 | CYP3A4 (0.55) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL31128828 | 0.76 | CYP3A4 (0.52) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL22677307 | 0.73 | CYP3A4 (0.50) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL29452527 | 0.73 | CYP3A4 (0.50) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL22658735 | 0.72 | CYP3A4 (0.64) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024208315-A1 | AROMATIC HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 中国医药研究开发中心有限公司 | 2024-10-10 | — | — | WO | disclosed |