Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 3/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.39 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.38 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28723884 | 0.84 | KCNQ3 (0.40) | SMN1; SMN2ALDH1A1KCNQ3KCNQ2KCNE1 | |
| SCHEMBL19776253 | 0.74 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1FAAHCYP3A4MAPK1 | |
| SCHEMBL20446748 | 0.73 | AAK1 (0.56) | CYP3A4TNIKABL1MAPT | |
| SCHEMBL487335 | 0.72 | ATM (0.51) | ALDH1A1MAPK1KDM4EMAPTKDR | |
| SCHEMBL31129256 | 0.72 | KCNQ3 (0.53) | SMN1; SMN2ALDH1A1KCNQ3KCNQ2KCNE1 | |
| SCHEMBL14007418 | 0.72 | KDM4E (0.33) | ALDH1A1CYP3A4MAPK1KCNQ3KCNQ2 | |
| SCHEMBL27837974 | 0.72 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1FAAHCYP3A4MAPK1 | |
| SCHEMBL20447299 | 0.71 | AAK1 (0.58) | SMN1; SMN2ABL1SRCKMT2A | |
| SCHEMBL31584353 | 0.71 | KMT2A (0.47) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL25231546 | 0.71 | BACE1 (0.33) | CYP3A4MAPK1KCNQ3KCNQ2KCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240309019-A1 | TRICYCLIC HETEROARYL-SUBSTITUTED QUINOLINE AND AZAQUINOLINE COMPOUNDS AS PAR4 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2024-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240309019-A1 | TRICYCLIC HETEROARYL-SUBSTITUTED QUINOLINE AND AZAQUINOLINE COMPOUNDS AS PAR4 INHIBITORS | F2RL3, PARP14, F2R | SMN1; SMN2 4221/4885ALDH1A1 2558/4885FAAH 1567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.