Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 3/20 | 0.47 |
| ▸ | PDE4A | P27815 | 2/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 10/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | INSR | P06213 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1410980 | 1.00 | PDE4D (0.47) | PDE4DPDE4APDE4BPDE4CFPR2 | |
| SCHEMBL3113212 | 1.00 | PDE4D (0.47) | PDE4DPDE4APDE4BPDE4CFPR2 | |
| Bromide SCHEMBL1410802 | 0.99 | PDE4D (0.46) | PDE4DPDE4APDE4BPDE4CFPR2 | |
| Hydrochloric Acid SCHEMBL1411323 | 0.99 | PDE4D (0.46) | PDE4DPDE4APDE4BPDE4CFPR2 | |
| Sulfuric Acid SCHEMBL1411243 | 0.96 | PDE4D (0.48) | PDE4DPDE4APDE4BPDE4CFPR2 | |
| Oxalic Acid SCHEMBL1411878 | 0.96 | PDE4D (0.48) | PDE4DPDE4APDE4BPDE4CFPR2 | |
| Fumaric Acid SCHEMBL1411070 | 0.93 | PDE4D (0.46) | PDE4DPDE4APDE4BPDE4CKDM4E | |
| Fumaric Acid SCHEMBL1411078 | 0.93 | PDE4D (0.46) | PDE4DPDE4APDE4BPDE4CKDM4E | |
| Cadaverine Tartrate SCHEMBL1410755 | 0.93 | PDE4D (0.47) | PDE4DPDE4APDE4BPDE4CKDM4E | |
| Alpha-Ketoglutaric Acid SCHEMBL1410828 | 0.91 | PDE4D (0.44) | PDE4DPDE4APDE4BPDE4CKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190818-A1 | Novel salts of 6-heterocycle substituted hexahydrophenanthridine derivatives | NYCOMED GMBH (DE) | 2010-07-29 | — | — | US | disclosed |