Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 7/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.48 |
| ▸ | AKT1 | P31749 | 7/20 | 0.42 |
| ▸ | LIMK2 | P53671 | 5/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | MAP3K6 | O95382 | 1/20 | 0.39 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21894377 | 0.98 | LIMK1 (0.49) | LIMK1ROCK2AKT1LIMK2JAK2 | |
| SCHEMBL28616421 | 0.97 | LIMK1 (0.48) | LIMK1ROCK2AKT1LIMK2JAK2 | |
| SCHEMBL31133380 | 0.82 | LIMK1 (0.47) | LIMK1ROCK2AKT1LIMK2JAK2 | |
| Potassium Ion SCHEMBL21818832 | 0.82 | LIMK1 (0.44) | LIMK1ROCK2AKT1LIMK2JAK3 | |
| SCHEMBL21818811 | 0.82 | LIMK1 (0.47) | LIMK1ROCK2AKT1LIMK2JAK2 | |
| SCHEMBL12590783 | 0.78 | NOTUM (0.56) | ROCK2AKT1JAK2JAK3MAP3K6 | |
| SCHEMBL21715878 | 0.78 | AKT1 (0.40) | LIMK1ROCK2AKT1JAK3TRPA1 | |
| SCHEMBL12590960 | 0.78 | NOTUM (0.37) | LIMK1ROCK2LIMK2JAK2JAK3 | |
| SCHEMBL10259826 | 0.74 | AKT1 (0.45) | LIMK1ROCK2AKT1TRPA1 | |
| SCHEMBL12590787 | 0.74 | CHUK (0.48) | ROCK2JAK3ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164459-B | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2024-09-03 | — | — | CN | disclosed |