Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 4/20 | 0.44 |
| ▸ | DGKA | P23743 | 4/20 | 0.43 |
| ▸ | DGKZ | Q13574 | 4/20 | 0.43 |
| ▸ | GPR6 | P46095 | 9/20 | 0.41 |
| ▸ | DGKI | O75912 | 1/20 | 0.36 |
| ▸ | DGKG | P49619 | 1/20 | 0.36 |
| ▸ | DGKK | Q5KSL6 | 1/20 | 0.36 |
| ▸ | DGKB | Q9Y6T7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23526837 | 1.00 | SCD (0.44) | SCDDGKADGKZGPR6DGKI | |
| SCHEMBL23526978 | 0.91 | SCD (0.53) | SCDDGKADGKZ | |
| SCHEMBL31133806 | 0.91 | SCD (0.53) | SCDDGKADGKZ | |
| SCHEMBL31133415 | 0.90 | SCD (0.45) | SCDDGKADGKZGPR6 | |
| SCHEMBL23526832 | 0.90 | SCD (0.45) | SCDDGKADGKZGPR6 | |
| SCHEMBL31133787 | 0.90 | SCD (0.45) | SCDDGKADGKZGPR6 | |
| SCHEMBL23527026 | 0.90 | SCD (0.45) | SCDDGKADGKZGPR6 | |
| SCHEMBL23527152 | 0.89 | SCD (0.46) | SCDDGKADGKZGPR6DGKI | |
| SCHEMBL23526885 | 0.89 | SCD (0.56) | SCDDGKADGKZ | |
| SCHEMBL31133573 | 0.89 | SCD (0.46) | SCDDGKADGKZGPR6DGKI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081523-B1 | SUBSTITUTED BICYCLIC PIPERIDINE DERIVATIVES USEFUL AS T CELL ACTIVATORS | BRISTOL MYERS SQUIBB CO (US) | 2024-12-25 | — | — | EP | claimed |
| CN-114901660-B | Substituted bicyclic compounds useful as T cell activators | 百时美施贵宝公司 | 2024-10-15 | — | — | CN | claimed |
| CN-114901660-B | Substituted bicyclic compounds useful as T cell activators | 百时美施贵宝公司 | 2024-10-15 | — | — | CN | disclosed |