Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 3/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | HNF4A | P41235 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5614218 | 0.82 | PTGER1 (0.51) | PTGER1PTGER4PTGER3PTGER2FOLH1 | |
| Bicarbonate SCHEMBL17473019 | 0.81 | FOLH1 (0.44) | PTGER1PTGER4PTGER3PTGER2FOLH1 | |
| SCHEMBL27742528 | 0.81 | PTGER1 (0.50) | PTGER1PTGER4PTGER3PTGER2FOLH1 | |
| SCHEMBL8696466 | 0.81 | CD274 (0.55) | PTGER1PTGER4PTGER3PTGER2FOLH1 | |
| Bicarbonate SCHEMBL17473105 | 0.80 | BID (0.49) | — | |
| SCHEMBL5139126 | 0.79 | DPP4 (0.50) | PTGER1PTGER4PTGER3PTGER2FOLH1 | |
| Bicarbonate SCHEMBL17473075 | 0.79 | BID (0.51) | — | |
| SCHEMBL6206188 | 0.78 | PTGER4 (0.58) | PTGER1PTGER4PTGER3PTGER2FOLH1 | |
| Bicarbonate SCHEMBL17473045 | 0.78 | FOLH1 (0.46) | PTGER1PTGER4PTGER3PTGER2FOLH1 | |
| SCHEMBL7707048 | 0.77 | PDCD1 (0.44) | FOLH1DPP4TLR8CD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101250133-B | Novel method for synthesizing (+/-)p-fluoro-2-(2-methyl-propionyl)-4-oxygen-N,3-diphenyl-benzenebutanamide and intermediate therein | INST MATERIA MEDICA CAMS | 2010-06-09 | — | — | CN | disclosed |
| EP-2170916-A1 | FURANOSE DERIVATIVES | Cbz Chemicals Limited (GB) | 2010-04-07 | — | — | EP | disclosed |
| WO-2008152386-A1 | FURANOSE DERIVATIVES | CBZ CHEMICALS LIMITED (GB) | 2008-12-18 | — | — | WO | disclosed |
| CN-101250133-A | Novel method for synthesizing (+/-)p-fluoro-2-(2-methyl-propionyl)-4-oxygen-N,3-diphenyl-benzenebutanamide and intermediate therein | INST MATERIA MEDICA CAMS (CN) | 2008-08-27 | — | — | CN | disclosed |