Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | YAP1 | P46937 | 2/20 | 0.41 |
| ▸ | TEAD4 | Q15561 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31139727 | 0.85 | MEN1 (0.54) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL31139719 | 0.84 | MEN1 (0.53) | MEN1KMT2AKDM4EYAP1TEAD4 | |
| SCHEMBL31139765 | 0.81 | MEN1 (0.53) | MEN1KMT2AKDM4EYAP1TEAD4 | |
| SCHEMBL31139705 | 0.81 | MEN1 (0.62) | MEN1KMT2AKDM4EALDH1A1YAP1 | |
| SCHEMBL31139728 | 0.81 | MEN1 (0.62) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL31139797 | 0.81 | MEN1 (0.47) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL31139778 | 0.81 | MEN1 (0.62) | MEN1KMT2AYAP1TEAD4NPC1 | |
| SCHEMBL31139693 | 0.81 | MEN1 (0.62) | MEN1KMT2AKDM4EALDH1A1YAP1 | |
| SCHEMBL31139699 | 0.79 | MEN1 (0.60) | MEN1KMT2AYAP1TEAD4NPC1 | |
| SCHEMBL31139720 | 0.79 | MEN1 (0.53) | MEN1KMT2AKDM4EYAP1TEAD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118696034-A | Novel bicyclic compounds as RAD51 inhibitors | 萨提亚疗法股份有限公司 | 2024-09-24 | — | — | CN | claimed |
| CN-118696034-A | Novel bicyclic compounds as RAD51 inhibitors | 萨提亚疗法股份有限公司 | 2024-09-24 | — | — | CN | disclosed |