Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 3/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | CIT | O14578 | 3/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.40 |
| ▸ | PRKACA | P17612 | 2/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.40 |
| ▸ | CDK9 | P50750 | 2/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | JAK3 | P52333 | 2/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | PAK4 | O96013 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25237197 | 1.00 | PRKCI (0.44) | PRKCIAXLCITALKROCK1 | |
| SCHEMBL76545 | 0.83 | PRKCI (0.47) | PRKCIAXLCITALKROCK1 | |
| SCHEMBL31140667 | 0.78 | ALK (0.40) | ALKROCK1PRKCQJAK2RET | |
| SCHEMBL25238925 | 0.78 | ALK (0.40) | ALKROCK1PRKCQJAK2RET | |
| SCHEMBL29100972 | 0.76 | ALK (0.39) | ALK | |
| SCHEMBL26686591 | 0.74 | CIT (0.45) | PRKCICITALKROCK1AURKB | |
| SCHEMBL1328052 | 0.73 | ROCK1 (0.41) | PRKCIAXLCITALKROCK1 | |
| SCHEMBL1329235 | 0.73 | CIT (0.44) | PRKCIAXLCITALKROCK1 | |
| SCHEMBL27829007 | 0.73 | ROCK1 (0.41) | PRKCIAXLCITALKROCK1 | |
| SCHEMBL1329786 | 0.73 | PRKCI (0.47) | PRKCIAXLALKROCK1AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118525018-A | Bialkyne compound and application thereof | 上海艾力斯医药科技股份有限公司 | 2024-08-20 | — | — | CN | disclosed |