SCHEMBL3114401

SCHEMBL3114401

O=C1NCN([C@H]2O[C@@H](CO)C(O)C2O)C(=O)N1

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CDA P32320 9/20 0.58
MAPT P10636 1/20 0.45
SLC28A1 O00337 1/20 0.44
SLC28A2 O43868 1/20 0.44
SLC29A1 Q99808 1/20 0.44
SLC28A3 Q9HAS3 1/20 0.44
PYGM P11217 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14509047 1.00 CDA (0.58) CDAMAPTSLC28A1SLC28A2SLC29A1
SCHEMBL3114394 1.00 CDA (0.58) CDAMAPTSLC28A1SLC28A2SLC29A1
SCHEMBL13519718 1.00 CDA (0.58) CDAMAPTSLC28A1SLC28A2SLC29A1
SCHEMBL399314 0.78 CDA (0.66) CDAMAPTSLC28A1SLC28A2SLC29A1
SCHEMBL30241991 0.78 CDA (0.66) CDAMAPTSLC28A1SLC28A2SLC29A1
SCHEMBL6015184 0.78 CDA (0.66) CDAMAPTSLC28A1SLC28A2SLC29A1
SCHEMBL11757296 0.78 CDA (0.66) CDAMAPTSLC28A1SLC28A2SLC29A1
SCHEMBL18512836 0.78 CDA (0.66) CDAMAPTSLC28A1SLC28A2SLC29A1
SCHEMBL18503564 0.78 CDA (0.66) CDAMAPTSLC28A1SLC28A2SLC29A1
SCHEMBL18512842 0.78 CDA (0.66) CDAMAPTSLC28A1SLC28A2SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7772197-B2 1,3,5-triazines for treatment of viral diseases 1,3,5-Triazines for Treatment of Viral Diseases (US) 2010-08-10 US disclosed
US-7642247-B2 1,3,5-triazines for treatment of viral diseases KORONIS PHARMACEUTICALS, INCORPORATED (US) 2010-01-05 US disclosed
US-20070207973-A1 1,3,5-Triazines for Treatment of Viral Diseases KORONIS PHARMACEUTICALS, INCORPORATED (US) 2007-09-06 US disclosed
US-20070142310-A1 1,3,5-TRIAZINES FOR TREATMENT OF VIRAL DISEASES KORONIS PHARMACEUTICALS, INCORPORATED (US) 2007-06-21 US disclosed
EP-1545558-A2 1, 3, 5-TRIAZINES FOR TREATMENT OF VIRAL DISEASES Koronis Pharmaceuticals, Inc. (US) 2005-06-29 EP disclosed
US-20040127436-A1 1,3,5-Triazines for treatment of viral diseases KORONIS PHARMACEUTICALS, INC. (US) 2004-07-01 US disclosed
WO-2004028454-A2 1, 3, 5-TRIAZINES FOR TREATMENT OF VIRAL DISEASES KORONIS PHARMACEUTICALS, INCORPORATED (US) 2004-04-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070207973-A1 1,3,5-Triazines for Treatment of Viral Diseases HAVCR2, EIF2AK2, IKZF3 CDA 688/4885MAPT 2447/4885SLC28A1 1923/4885
US-20070142310-A1 1,3,5-TRIAZINES FOR TREATMENT OF VIRAL DISEASES HAVCR2, EIF2AK2, IKZF3 CDA 688/4885MAPT 2447/4885SLC28A1 1923/4885
US-20040127436-A1 1,3,5-Triazines for treatment of viral diseases HAVCR2, EIF2AK2, IKZF3 CDA 688/4885MAPT 2447/4885SLC28A1 1923/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.