Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RGS12 | O14924 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 4/20 | 0.44 |
| ▸ | BCHE | P06276 | 4/20 | 0.43 |
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31146763 | 0.92 | FGFR1 (0.46) | FGFR1KDRPDGFRAMAPK1MEN1 | |
| SCHEMBL31146787 | 0.88 | FGFR1 (0.48) | FGFR1KDRPDGFRAMAPK1MEN1 | |
| SCHEMBL31146703 | 0.86 | FGFR1 (0.48) | FGFR1KDRPDGFRAMAPK1MEN1 | |
| SCHEMBL31146757 | 0.86 | FGFR1 (0.50) | FGFR1KDRPDGFRAMAPK1MEN1 | |
| SCHEMBL20735100 | 0.82 | MEN1 (0.60) | FGFR1KDRPDGFRAMAPK1MEN1 | |
| SCHEMBL31146821 | 0.81 | RXFP1 (0.47) | FGFR1KDRPDGFRAMAPK1MEN1 | |
| SCHEMBL31146776 | 0.81 | FGFR1 (0.53) | FGFR1KDRPDGFRAMAPK1MEN1 | |
| SCHEMBL20735155 | 0.81 | MEN1 (0.58) | FGFR1KDRPDGFRAMAPK1MEN1 | |
| SCHEMBL20726222 | 0.81 | MEN1 (0.58) | FGFR1KDRPDGFRAMAPK1MEN1 | |
| SCHEMBL20735101 | 0.77 | MEN1 (0.62) | FGFR1KDRPDGFRAMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118724811-A | Preparation method and application of aldehyde group-containing substituted naphthalimide derivative | 中国医学科学院药物研究所 | 2024-10-01 | — | — | CN | disclosed |