Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 19/20 | 0.52 |
| ▸ | HSP90AB1 | P08238 | 19/20 | 0.52 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.42 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31146880 | 0.89 | HSP90AA1 (0.60) | HSP90AA1HSP90AB1HSP90B1ERBB2TRAP1 | |
| SCHEMBL31146859 | 0.88 | HSP90AB1 (0.51) | HSP90AA1HSP90AB1HSP90B1ERBB2TRAP1 | |
| SCHEMBL31146878 | 0.78 | HSP90AA1 (0.33) | HSP90AA1HSP90AB1HSP90B1ERBB2 | |
| SCHEMBL11980471 | 0.77 | HSP90AA1 (0.74) | HSP90AA1HSP90AB1HSP90B1ERBB2TRAP1 | |
| SCHEMBL31146862 | 0.77 | HSP90AA1 (0.62) | HSP90AA1HSP90AB1HSP90B1ERBB2TRAP1 | |
| SCHEMBL13737330 | 0.72 | HSP90AA1 (0.77) | HSP90AA1HSP90AB1HSP90B1ERBB2TRAP1 | |
| SCHEMBL13519938 | 0.69 | HSP90AA1 (0.78) | HSP90AA1HSP90AB1ERBB2 | |
| SCHEMBL1669706 | 0.69 | HSP90AB1 (0.68) | HSP90AA1HSP90AB1HSP90B1ERBB2TRAP1 | |
| SCHEMBL13193779 | 0.68 | HSP90AA1 (0.78) | HSP90AA1HSP90AB1HSP90B1ERBB2TRAP1 | |
| SCHEMBL15473381 | 0.67 | HSP90AA1 (0.77) | HSP90AA1HSP90AB1HSP90B1ERBB2TRAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4680606-A1 | ADENINE DERIVATIVES AS HSP90 INHIBITORS | AtmosR (FR) | 2026-01-21 | — | — | EP | disclosed |
| WO-2024194175-A1 | ADENINE DERIVATIVES AS HSP90 INHIBITORS | ATMOSR (FR) | 2024-09-26 | — | — | WO | disclosed |