Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 18/20 | 0.70 |
| ▸ | MTOR | P42345 | 7/20 | 0.70 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.70 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.52 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.52 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.49 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31147861 | 0.82 | PIK3CA (1.00) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL1114177 | 0.82 | PIK3CA (1.00) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL805107 | 0.78 | PIK3CA (0.62) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL1113988 | 0.77 | PIK3CA (0.71) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL1114044 | 0.77 | PIK3CA (0.90) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL336657 | 0.77 | PIK3CA (0.61) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL1114247 | 0.75 | PIK3CA (0.86) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL1114156 | 0.74 | PIK3CA (0.73) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL1114139 | 0.73 | PIK3CA (1.00) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL16411763 | 0.73 | PIK3CA (0.84) | PIK3CAMTORPIK3CDPIK3CGPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4694893-A1 | NOVEL INHIBITORS OF PIKFYVE AND METHODS USING SAME | TME Therapeutics LLC (US) | 2026-02-18 | — | — | EP | claimed |
| WO-2024216229-A1 | NOVEL INHIBITORS OF PIKFYVE AND METHODS USING SAME | TME THERAPEUTICS LLC (US) | 2024-10-17 | — | — | WO | claimed |