Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PFKFB3 | Q16875 | 4/20 | 0.53 |
| ▸ | PFKFB2 | O60825 | 3/20 | 0.53 |
| ▸ | PFKFB1 | P16118 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGAV | P06756 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23373313 | 1.00 | PFKFB3 (0.53) | PFKFB3PFKFB2PFKFB1ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL31148145 | 0.99 | PFKFB3 (0.52) | PFKFB3PFKFB2PFKFB1ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL31148193 | 0.99 | PFKFB3 (0.52) | PFKFB3PFKFB2PFKFB1ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL31148182 | 0.99 | PFKFB3 (0.52) | PFKFB3PFKFB2PFKFB1ALDH1A1HTT | |
| SCHEMBL31148274 | 0.97 | KMT2A (0.51) | PFKFB3PFKFB2PFKFB1ALDH1A1HTT | |
| SCHEMBL31148228 | 0.97 | KMT2A (0.51) | PFKFB3PFKFB2PFKFB1ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL31148158 | 0.96 | KMT2A (0.50) | PFKFB3PFKFB2PFKFB1ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL31148291 | 0.96 | KMT2A (0.50) | PFKFB3PFKFB2PFKFB1ALDH1A1HTT | |
| SCHEMBL23373335 | 0.87 | PFKFB3 (0.53) | PFKFB3PFKFB2PFKFB1ALDH1A1HPGD | |
| SCHEMBL23373378 | 0.87 | PFKFB3 (0.61) | PFKFB3PFKFB2PFKFB1NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4695236-A1 | SUBSTITUTED PHENYL-PIPERAZINYL BASED MODULATORS FOR THE TREATMENT OF DISEASE | Soley Therapeutics, Inc. (US) | 2026-02-18 | — | — | EP | disclosed |
| WO-2024216094-A1 | SUBSTITUTED PHENYL-PIPERAZINYL BASED MODULATORS FOR THE TREATMENT OF DISEASE | SOLEY THERAPEUTICS, INC. (US) | 2024-10-17 | — | — | WO | disclosed |