⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27679001 | 0.86 | CYP1A2 (0.57) | — | |
| SCHEMBL4464939 | 0.83 | GAA (0.59) | — | |
| SCHEMBL16935737 | 0.83 | CYP1A2 (0.53) | — | |
| SCHEMBL13756031 | 0.81 | GAA (0.56) | — | |
| Hydrochloric Acid SCHEMBL11851530 | 0.81 | GAA (0.56) | — | |
| SCHEMBL498980 | 0.81 | — | — | |
| SCHEMBL3096968 | 0.81 | — | — | |
| SCHEMBL11508859 | 0.80 | GAA (0.50) | — | |
| SCHEMBL2906712 | 0.80 | GAA (0.50) | — | |
| SCHEMBL3834822 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140256783-A1 | SUBSTRATE AND METHOD FOR PRODUCTION THEREOF | TORAY INDUSTRIES, INC. (JP) | 2014-09-11 | — | — | US | claimed |
| EP-2183253-B1 | THIENO-PYRIDINE DERIVATIVES AS MEK INHIBITORS | UCB PHARMA SA (BE) | 2013-12-18 | — | — | EP | claimed |
| EP-2072070-B1 | SUBSTRATE AND METHOD FOR PRODUCTION THEREOF | TORAY INDUSTRIES (JP) | 2016-11-09 | — | — | EP | disclosed |
| US-20140256783-A1 | SUBSTRATE AND METHOD FOR PRODUCTION THEREOF | TORAY INDUSTRIES, INC. (JP) | 2014-09-11 | — | — | US | disclosed |
| US-8733557-B2 | Substrate and method for production thereof | TORAY INDUSTRIES, INC. (JP) | 2014-05-27 | — | — | US | disclosed |
| EP-2183253-B1 | THIENO-PYRIDINE DERIVATIVES AS MEK INHIBITORS | UCB PHARMA SA (BE) | 2013-12-18 | — | — | EP | disclosed |
| US-8350037-B2 | Thieno-pyridine derivatives as MEK inhibitors | UCB PHARMA, S.A. (BE) | 2013-01-08 | — | — | US | disclosed |
| US-20100179124-A1 | THIENO-PYRIDINE DERIVATIVES AS MEK INHIBITORS | UCB PHARMA S.A. (BE) | 2010-07-15 | — | — | US | disclosed |
| US-20100176048-A1 | Substrate and method for production thereof | TORAY INDUSTRIES, INC. (JP) | 2010-07-15 | — | — | US | disclosed |
| EP-2183253-A1 | THIENO-PYRIDINE DERIVATIVES AS MEK INHIBITORS | UCB Pharma, S.A. (BE) | 2010-05-12 | — | — | EP | disclosed |
| EP-2072070-A1 | SUBSTRATE AND METHOD FOR PRODUCTION THEREOF | Toray Industries, Inc. (JP) | 2009-06-24 | — | — | EP | disclosed |
| WO-2009013462-A1 | THIENO-PYRIDINE DERIVATIVES AS MEK INHIBITORS | UCB PHARMA S.A. (BE) | 2009-01-29 | — | — | WO | disclosed |