Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCND1 | P24385 | 20/20 | 1.00 |
| ▸ | CCNE1 | P24864 | 20/20 | 1.00 |
| ▸ | CDK2 | P24941 | 20/20 | 1.00 |
| ▸ | CDK6 | Q00534 | 20/20 | 1.00 |
| ▸ | CDK4 | P11802 | 5/20 | 1.00 |
| ▸ | CCND3 | P30281 | 4/20 | 1.00 |
| ▸ | CCNT1 | O60563 | 3/20 | 1.00 |
| ▸ | CDK9 | P50750 | 3/20 | 1.00 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.78 |
| ▸ | RB1 | P06400 | 1/20 | 0.78 |
| ▸ | CDK1 | P06493 | 1/20 | 0.78 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19857329 | 1.00 | CCND1 (1.00) | CCND1CCNE1CDK2CDK6CDK4 | |
| SCHEMBL19863682 | 1.00 | CCND1 (1.00) | CCND1CCNE1CDK2CDK6CDK4 | |
| SCHEMBL19857331 | 0.94 | CCND1 (1.00) | CCND1CCNE1CDK2CDK6CDK4 | |
| SCHEMBL22787395 | 0.94 | CCND1 (1.00) | CCND1CCNE1CDK2CDK6CDK4 | |
| SCHEMBL19863658 | 0.94 | CCND1 (1.00) | CCND1CCNE1CDK2CDK6CDK4 | |
| SCHEMBL19868173 | 0.92 | CCNE1 (1.00) | CCND1CCNE1CDK2CDK6CDK4 | |
| SCHEMBL19857364 | 0.92 | CCNE1 (1.00) | CCND1CCNE1CDK2CDK6CDK4 | |
| SCHEMBL19863698 | 0.91 | CCNE1 (1.00) | CCND1CCNE1CDK2CDK6CDK4 | |
| SCHEMBL19863697 | 0.91 | CCNE1 (1.00) | CCND1CCNE1CDK2CDK6CDK4 | |
| SCHEMBL25316105 | 0.90 | CCNE1 (1.00) | CCND1CCNE1CDK2CDK6CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114394966-B | Pyridopyrimidinone CDK2/4/6 inhibitors | 辉瑞公司 | 2024-10-11 | — | — | CN | disclosed |