Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCND1 | P24385 | 15/20 | 0.55 |
| ▸ | CDK2 | P24941 | 15/20 | 0.55 |
| ▸ | CDK4 | P11802 | 9/20 | 0.55 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.55 |
| ▸ | CCND3 | P30281 | 4/20 | 0.53 |
| ▸ | CCND2 | P30279 | 3/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.48 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.48 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.48 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.48 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 10/20 | 0.40 |
| ▸ | CDK6 | Q00534 | 8/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.40 |
| ▸ | CDK9 | P50750 | 3/20 | 0.40 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4830604 | 1.00 | CCND1 (0.55) | CCND1CDK2CDK4CCNA2CCND3 | |
| SCHEMBL4833696 | 0.99 | CCND1 (0.54) | CCND1CDK2CDK4CCNA2CCND3 | |
| SCHEMBL22200529 | 0.95 | CCND1 (0.49) | CCND1CDK2CDK4CCNA2CCND3 | |
| SCHEMBL4828668 | 0.87 | CDK2 (0.53) | CCND1CDK2CDK4CCNA2CCND3 | |
| SCHEMBL4826681 | 0.87 | CCND1 (0.48) | CCND1CDK2CDK4CCNA2CCND3 | |
| SCHEMBL29507751 | 0.85 | CDK2 (0.40) | CCND1CDK2CDK4CCNA2CCND3 | |
| SCHEMBL4835866 | 0.85 | CCND1 (0.54) | CCND1CDK2CDK4CCNA2CCND3 | |
| SCHEMBL31073291 | 0.83 | CDK2 (0.56) | CCND1CDK2CDK4CCNA2CCND3 | |
| SCHEMBL22015971 | 0.83 | NUAK1 (0.56) | CCND1CDK2CDK4CCNA2CCND3 | |
| SCHEMBL29507954 | 0.83 | NUAK1 (0.56) | CCND1CDK2CDK4CCNA2CCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114394966-B | Pyridopyrimidinone CDK2/4/6 inhibitors | 辉瑞公司 | 2024-10-11 | — | — | CN | disclosed |