Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 3/20 | 0.45 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16077836 | 0.70 | PLAT (0.47) | PLATKDM4DKDM5AKDM4EALDH1A1 | |
| SCHEMBL17547885 | 0.68 | KDM5A (0.40) | PLATKDM4DKDM5AKDM4EALDH1A1 | |
| SCHEMBL16050559 | 0.68 | PLAT (0.42) | PLATKDM4DKDM5AKDM4EALDH1A1 | |
| SCHEMBL16046782 | 0.67 | KDM5A (0.57) | PLATKDM4DKDM5AKDM4EALDH1A1 | |
| SCHEMBL16077834 | 0.67 | KDM5A (0.53) | PLATKDM4DKDM5AKDM4EALDH1A1 | |
| SCHEMBL14994328 | 0.67 | PLAT (0.53) | PLATKDM4DKDM5A | |
| SCHEMBL16046587 | 0.67 | KDM4D (0.50) | PLATKDM4DKDM4EALDH1A1GAA | |
| SCHEMBL4216536 | 0.67 | KDM4D (0.59) | PLATKDM4DKDM4EALDH1A1HPGD | |
| SCHEMBL16046503 | 0.67 | PLAT (0.44) | PLATKDM4DKDM4EALDH1A1 | |
| SCHEMBL16047129 | 0.66 | KDM5A (0.50) | PLATKDM4DKDM5AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220399-A1 | PYRAZOLOTRIAZINECARBONITRILES USEFUL AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-10-24 | — | — | WO | disclosed |