Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | BRD4 | O60885 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | DAO | P14920 | 1/20 | 0.56 |
| ▸ | DDO | Q99489 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | IL4I1 | Q96RQ9 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1263927 | 1.00 | KDM4E (0.66) | KDM4EALDH1A1MAPTHPGDBRD4 | |
| Bicarbonate SCHEMBL6993932 | 0.93 | MAPK1 (0.61) | KDM4EALDH1A1MAPTHPGDBRD4 | |
| SCHEMBL13349416 | 0.87 | KDM4E (0.59) | KDM4EALDH1A1MAPTHPGDBRD4 | |
| SCHEMBL26761838 | 0.83 | KDM4E (0.69) | KDM4EALDH1A1MAPTHPGDBRD4 | |
| SCHEMBL1370758 | 0.83 | KDM4E (0.59) | KDM4EALDH1A1MAPTHPGDBRD4 | |
| SCHEMBL30162531 | 0.83 | KDM4E (0.58) | KDM4EALDH1A1MAPTHPGDBRD4 | |
| SCHEMBL9293635 | 0.83 | KDM4E (0.58) | KDM4EALDH1A1MAPTHPGDBRD4 | |
| SCHEMBL6402311 | 0.83 | DAO (0.59) | KDM4EALDH1A1HPGDBRD4HSD17B10 | |
| SCHEMBL17618004 | 0.83 | KDM4E (0.58) | KDM4EALDH1A1MAPTHPGDBRD4 | |
| SCHEMBL8873594 | 0.83 | KDM4E (0.58) | KDM4EALDH1A1MAPTHPGDBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025101892-A1 | POLY-ADP RIBOSE POLYMERASE (PARP) INHIBITORS AND USES THEREOF | Astellas Engineered Small Molecules US, Incorporated (US) | 2025-05-15 | — | — | WO | disclosed |
| US-20240400784-A1 | Method for Screening Solvent for Extracting Polyvinyl Chloride, Method for Recycling Waste, Recycled Polyvinyl Chloride, and Composition | LG CHEM, LTD. (KR) | 2024-12-05 | — | — | US | disclosed |
| CN-118754853-A | Preparation method and application of sulfonamide compound with BRD4 and PARP1 double-target inhibition effect | 扬州大学 | 2024-10-11 | — | — | CN | disclosed |