Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.57 |
| ▸ | BTK | Q06187 | 1/20 | 0.51 |
| ▸ | INSR | P06213 | 2/20 | 0.46 |
| ▸ | IGF1R | P08069 | 2/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31155382 | 0.95 | EGFR (0.63) | EGFRBTKINSRIGF1RALK | |
| SCHEMBL31155604 | 0.94 | EGFR (0.57) | EGFRBTKINSRIGF1RALK | |
| SCHEMBL31155520 | 0.90 | EGFR (0.55) | EGFRBTKINSRIGF1RALK | |
| Hydrochloric Acid SCHEMBL31155442 | 0.87 | EGFR (0.54) | EGFRBTK | |
| Hydrochloric Acid SCHEMBL31155471 | 0.86 | EGFR (0.58) | EGFRBTKINSRIGF1RALK | |
| SCHEMBL31155590 | 0.86 | EGFR (0.67) | EGFRBTKINSRIGF1RALK | |
| SCHEMBL31155359 | 0.84 | EGFR (0.66) | EGFRBTKINSRIGF1RALK | |
| SCHEMBL31155376 | 0.83 | EGFR (0.64) | EGFRBTKINSRIGF1RALK | |
| Hydrochloric Acid SCHEMBL31155447 | 0.83 | EGFR (0.56) | EGFRBTKINSRIGF1RALK | |
| SCHEMBL31155381 | 0.83 | EGFR (0.55) | EGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024217481-A1 | EGFR DEGRADING AGENT, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 上海齐鲁制药研究中心有限公司 | 2024-10-24 | — | — | WO | disclosed |