Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.52 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31155533 | 0.98 | EGFR (0.51) | EGFRBTK | |
| SCHEMBL31155507 | 0.98 | EGFR (0.51) | EGFRBTK | |
| SCHEMBL31155405 | 0.95 | EGFR (0.58) | EGFRBTK | |
| SCHEMBL31155413 | 0.94 | EGFR (0.61) | EGFRBTK | |
| SCHEMBL31155446 | 0.94 | EGFR (0.52) | EGFRBTK | |
| SCHEMBL31155425 | 0.94 | EGFR (0.52) | EGFRBTK | |
| SCHEMBL31155583 | 0.93 | EGFR (0.52) | EGFRBTK | |
| SCHEMBL31155564 | 0.93 | EGFR (0.51) | EGFRBTK | |
| SCHEMBL31155581 | 0.93 | EGFR (0.52) | EGFRBTK | |
| SCHEMBL31155612 | 0.92 | EGFR (0.51) | EGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024217481-A1 | EGFR DEGRADING AGENT, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 上海齐鲁制药研究中心有限公司 | 2024-10-24 | — | — | WO | disclosed |