Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.64 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | ASIC3 | Q9UHC3 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.48 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.48 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4257668 | 0.89 | ADORA2A (0.67) | ADORA2AADORA1MEN1KMT2AASIC3 | |
| SCHEMBL19417187 | 0.84 | MEN1 (0.64) | ADORA2AADORA1MEN1KMT2AASIC3 | |
| SCHEMBL4257749 | 0.83 | MEN1 (0.79) | ADORA2AADORA1MEN1KMT2AASIC3 | |
| SCHEMBL19417245 | 0.81 | MEN1 (0.83) | ADORA2AADORA1MEN1KMT2AASIC3 | |
| SCHEMBL19417164 | 0.81 | MEN1 (0.83) | ADORA2AADORA1MEN1KMT2AASIC3 | |
| SCHEMBL29814953 | 0.81 | ADORA2A (0.42) | ADORA2AADORA1MEN1KMT2AASIC3 | |
| SCHEMBL14927901 | 0.79 | ADORA2A (0.55) | ADORA2AADORA1MEN1KMT2AASIC3 | |
| SCHEMBL19059887 | 0.79 | ADORA2A (0.55) | ADORA2AADORA1MEN1KMT2AASIC3 | |
| SCHEMBL3350943 | 0.79 | KDM4E (0.67) | ADORA2AADORA1MEN1KMT2AASIC3 | |
| SCHEMBL4262493 | 0.79 | ADORA2A (0.60) | ADORA2AADORA1MEN1KMT2AASIC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118791418-A | Indole compound and preparation method and application thereof | 纽欧申医药(上海)有限公司 | 2024-10-18 | — | — | CN | disclosed |
| WO-2024213032-A1 | INDOLE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | 纽欧申医药(上海)有限公司 | 2024-10-17 | — | — | WO | disclosed |