Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.61 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.59 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.49 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.49 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.49 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.49 |
| ▸ | IKZF2 | Q9UKS7 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31159092 | 0.96 | CRBN (0.64) | CRBNCSNK1A1MAP1LC3BIKZF1GSPT1 | |
| SCHEMBL31159058 | 0.94 | CRBN (0.59) | CRBNCSNK1A1MAP1LC3BIKZF1GSPT1 | |
| SCHEMBL31158811 | 0.94 | CRBN (0.66) | CRBNCSNK1A1MAP1LC3BIKZF1IKZF2 | |
| SCHEMBL31159123 | 0.87 | CRBN (0.56) | CRBNCSNK1A1IKZF1GSPT1DDB1 | |
| SCHEMBL31158641 | 0.87 | CRBN (0.65) | CRBNCSNK1A1GSPT1DDB1IKZF3 | |
| SCHEMBL31158864 | 0.86 | CRBN (0.64) | CRBNCSNK1A1GSPT1DDB1IKZF3 | |
| SCHEMBL31158793 | 0.86 | CRBN (0.64) | CRBNCSNK1A1GSPT1DDB1IKZF3 | |
| SCHEMBL31158764 | 0.86 | CRBN (0.60) | CRBNCSNK1A1MAP1LC3BIKZF1IKZF2 | |
| SCHEMBL31158956 | 0.85 | CRBN (0.61) | CRBNCSNK1A1GSPT1DDB1IKZF3 | |
| SCHEMBL31158865 | 0.85 | CRBN (0.63) | CRBNCSNK1A1GSPT1DDB1IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024201248-A1 | COMPOUNDS AND METHODS FOR DEGRADING GSPT1 | PIN THERAPEUTICS, INC. (KR) | 2024-10-03 | — | — | WO | disclosed |