Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.34 |
| ▸ | PARP11 | Q9NR21 | 3/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31161874 | 0.85 | PARP10 (0.32) | PARP10PARP11 | |
| SCHEMBL31161543 | 0.85 | PARP10 (0.32) | PARP10PARP11 | |
| SCHEMBL31161725 | 0.80 | S1PR1 (0.42) | S1PR1S1PR3PARP10PARP11PARP1 | |
| SCHEMBL31161709 | 0.78 | S1PR1 (0.36) | S1PR1S1PR3PARP10PARP11PARP1 | |
| SCHEMBL31161954 | 0.78 | S1PR1 (0.36) | S1PR1S1PR3PARP10PARP11PARP1 | |
| SCHEMBL31162087 | 0.76 | S1PR1 (0.35) | S1PR1S1PR3HTR5ABCHEACHE | |
| SCHEMBL31218654 | 0.75 | S1PR1 (0.36) | S1PR1S1PR3PARP10PARP11PARP1 | |
| SCHEMBL31161276 | 0.70 | S1PR1 (0.36) | S1PR1S1PR3PARP10PARP11PARP1 | |
| Trifluoroacetic Acid SCHEMBL26097973 | 0.70 | HDAC1 (0.34) | S1PR1S1PR3PARP10PARP11PARP1 | |
| SCHEMBL20539302 | 0.69 | NOTUM (0.47) | S1PR1S1PR3PARP10PARP11PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125400-A1 | TYK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS INC (US) | 2026-05-07 | — | — | US | disclosed |
| WO-2024220937-A2 | TYK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125400-A1 | TYK2 DEGRADERS AND USES THEREOF | TYK2, CSNK2A1, CSNK2A2 | S1PR1 3629/4885S1PR3 3749/4885P2RX7 3438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.