Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31161236 | 0.95 | TYK2 (0.31) | TYK2 | |
| SCHEMBL31161459 | 0.95 | TYK2 (0.35) | TYK2 | |
| SCHEMBL30391637 | 0.94 | TYK2 (0.33) | TYK2 | |
| SCHEMBL26099972 | 0.94 | TYK2 (0.33) | TYK2 | |
| SCHEMBL35210506 | 0.88 | TYK2 (0.32) | TYK2 | |
| SCHEMBL31161405 | 0.86 | F10 (0.36) | TYK2 | |
| SCHEMBL31161517 | 0.86 | TYK2 (0.33) | TYK2 | |
| SCHEMBL31161283 | 0.86 | F10 (0.33) | — | |
| SCHEMBL31161617 | 0.86 | F10 (0.33) | — | |
| SCHEMBL30392469 | 0.84 | TYK2 (0.35) | TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220937-A2 | TYK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |