Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 7/20 | 0.62 |
| ▸ | BRD4 | O60885 | 10/20 | 0.60 |
| ▸ | JAK1 | P23458 | 9/20 | 0.60 |
| ▸ | JAK3 | P52333 | 6/20 | 0.60 |
| ▸ | TYK2 | P29597 | 4/20 | 0.60 |
| ▸ | RET | P07949 | 3/20 | 0.60 |
| ▸ | WEE1 | P30291 | 3/20 | 0.60 |
| ▸ | FLT3 | P36888 | 3/20 | 0.60 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.60 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.60 |
| ▸ | NUAK1 | O60285 | 2/20 | 0.60 |
| ▸ | PLK4 | O00444 | 2/20 | 0.60 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.60 |
| ▸ | AURKA | O14965 | 2/20 | 0.60 |
| ▸ | DCLK1 | O15075 | 2/20 | 0.60 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.60 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.60 |
| ▸ | PAK4 | O96013 | 2/20 | 0.60 |
| ▸ | ABL1 | P00519 | 2/20 | 0.60 |
| ▸ | EGFR | P00533 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30565216 | 0.94 | JAK2 (0.67) | JAK2BRD4JAK1JAK3TYK2 | |
| SCHEMBL25381399 | 0.94 | JAK2 (0.67) | JAK2BRD4JAK1JAK3TYK2 | |
| SCHEMBL31163131 | 0.90 | JAK2 (0.62) | JAK2BRD4JAK1JAK3TYK2 | |
| SCHEMBL20288209 | 0.88 | JAK2 (0.75) | JAK2BRD4JAK1JAK3TYK2 | |
| SCHEMBL30565204 | 0.87 | BRD4 (0.74) | JAK2BRD4JAK1JAK3TYK2 | |
| SCHEMBL30565206 | 0.87 | BRD4 (0.74) | JAK2BRD4JAK1JAK3TYK2 | |
| SCHEMBL25382998 | 0.87 | BRD4 (0.74) | JAK2BRD4JAK1JAK3TYK2 | |
| SCHEMBL31163087 | 0.85 | JAK2 (0.63) | JAK2BRD4JAK1JAK3TYK2 | |
| SCHEMBL13031088 | 0.84 | BRD4 (0.73) | JAK2BRD4JAK1JAK3TYK2 | |
| SCHEMBL31163079 | 0.84 | JAK2 (0.66) | JAK2BRD4JAK1JAK3TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4673149-A1 | NEW COMPOUNDS AND TREATMENT OF RENAL CELL CARCINOMA | Trustlife Global Inc. (US) | 2026-01-07 | — | — | EP | disclosed |
| WO-2024179699-A1 | NEW COMPOUNDS AND TREATMENT OF RENAL CELL CARCINOMA | BASH BIOTECH INC. (US) | 2024-09-06 | — | — | WO | disclosed |