SCHEMBL31163056

SCHEMBL31163056

Cc1cnc(Nc2ccc(N3CCN(C)CC3)cc2)nc1Nc1ccc(N2CCOCC2)cc1

nearest known ligand 0.76

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 16/20 0.76
EGFR P00533 1/20 0.68
PDGFRB P09619 1/20 0.68
PDGFRA P16234 1/20 0.68
JAK2 O60674 1/20 0.67
FLT3 P36888 1/20 0.67
SYK P43405 1/20 0.65
ALK Q9UM73 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL270435 0.87 BRD4 (0.76) BRD4EGFR
SCHEMBL12278146 0.87 BRD4 (0.68) BRD4EGFRJAK2FLT3ALK
SCHEMBL12111070 0.86 BRD4 (0.73) BRD4EGFRJAK2FLT3
Hydrochloric Acid SCHEMBL266755 0.86 BRD4 (0.74) BRD4EGFR
SCHEMBL17526244 0.86 BRD4 (1.00) BRD4EGFR
SCHEMBL30306570 0.86 BRD4 (1.00) BRD4EGFR
SCHEMBL24426202 0.86 SYK (0.62) BRD4PDGFRBPDGFRASYK
SCHEMBL270552 0.85 BRD4 (0.80) BRD4EGFRALK
SCHEMBL17915974 0.84 BRD4 (0.78) BRD4JAK2FLT3ALK
SCHEMBL12277255 0.84 PDGFRB (0.69) BRD4PDGFRBPDGFRASYK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4673149-A1 NEW COMPOUNDS AND TREATMENT OF RENAL CELL CARCINOMA Trustlife Global Inc. (US) 2026-01-07 EP disclosed
WO-2024179699-A1 NEW COMPOUNDS AND TREATMENT OF RENAL CELL CARCINOMA BASH BIOTECH INC. (US) 2024-09-06 WO disclosed