Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 11/20 | 0.74 |
| ▸ | JAK1 | P23458 | 8/20 | 0.74 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.74 |
| ▸ | JAK2 | O60674 | 7/20 | 0.71 |
| ▸ | JAK3 | P52333 | 5/20 | 0.68 |
| ▸ | RET | P07949 | 3/20 | 0.68 |
| ▸ | WEE1 | P30291 | 3/20 | 0.68 |
| ▸ | FLT3 | P36888 | 3/20 | 0.68 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.68 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.68 |
| ▸ | BUB1B | O60566 | 1/20 | 0.68 |
| ▸ | BRD2 | P25440 | 1/20 | 0.68 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.68 |
| ▸ | TYK2 | P29597 | 4/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.66 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.66 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.66 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.66 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30565222 | 0.93 | BRD4 (0.74) | BRD4JAK1HDAC1JAK2JAK3 | |
| SCHEMBL25382552 | 0.93 | BRD4 (0.74) | BRD4JAK1HDAC1JAK2JAK3 | |
| SCHEMBL30565200 | 0.91 | JAK1 (0.81) | BRD4JAK1HDAC1JAK2JAK3 | |
| SCHEMBL25383521 | 0.91 | JAK1 (0.81) | BRD4JAK1HDAC1JAK2JAK3 | |
| SCHEMBL28657345 | 0.91 | BRD4 (0.77) | BRD4JAK1HDAC1JAK2JAK3 | |
| SCHEMBL25382998 | 0.90 | BRD4 (0.74) | BRD4JAK1HDAC1JAK2JAK3 | |
| SCHEMBL30565206 | 0.90 | BRD4 (0.74) | BRD4JAK1HDAC1JAK2JAK3 | |
| SCHEMBL30565204 | 0.90 | BRD4 (0.74) | BRD4JAK1HDAC1JAK2JAK3 | |
| SCHEMBL13031046 | 0.89 | BRD4 (0.74) | BRD4JAK1HDAC1JAK2JAK3 | |
| SCHEMBL13031088 | 0.89 | BRD4 (0.73) | BRD4JAK1HDAC1JAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4673149-A1 | NEW COMPOUNDS AND TREATMENT OF RENAL CELL CARCINOMA | Trustlife Global Inc. (US) | 2026-01-07 | — | — | EP | disclosed |
| WO-2024179699-A1 | NEW COMPOUNDS AND TREATMENT OF RENAL CELL CARCINOMA | BASH BIOTECH INC. (US) | 2024-09-06 | — | — | WO | disclosed |