Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 15/20 | 0.42 |
| ▸ | UGCG | Q16739 | 15/20 | 0.42 |
| ▸ | GBA2 | Q9HCG7 | 15/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LCT | P09848 | 4/20 | 0.40 |
| ▸ | MGAM | O43451 | 2/20 | 0.40 |
| ▸ | SI | P14410 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31163875 | 0.90 | UGCG (0.45) | GBA1UGCGGBA2LCTMGAM | |
| Hydrochloric Acid SCHEMBL31163788 | 0.87 | UGCG (0.42) | GBA1UGCGGBA2LCTMGAM | |
| SCHEMBL31163796 | 0.85 | UGCG (0.55) | GBA1UGCGGBA2KDM4EALDH1A1 | |
| SCHEMBL31163825 | 0.85 | UGCG (0.53) | GBA1UGCGGBA2LCTMGAM | |
| SCHEMBL31163903 | 0.85 | UGCG (0.53) | GBA1UGCGGBA2LCTMGAM | |
| SCHEMBL31163888 | 0.84 | GBA2 (0.42) | GBA1UGCGGBA2LCTMGAM | |
| Hydrochloric Acid SCHEMBL31163915 | 0.84 | UGCG (0.51) | GBA1UGCGGBA2KDM4ELCT | |
| SCHEMBL31163933 | 0.83 | GBA2 (0.43) | GBA1UGCGGBA2LCTMGAM | |
| SCHEMBL31163920 | 0.83 | GBA2 (0.43) | GBA1UGCGGBA2LCTMGAM | |
| SCHEMBL31163846 | 0.83 | UGCG (0.53) | GBA1UGCGGBA2LCTMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024179491-A1 | GBA1 AND GCS DUAL MODULATOR | ONO PHARMACEUTICAL CO., LTD. (JP) | 2024-09-06 | — | — | WO | disclosed |