Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31163848 | 0.94 | SMN1; SMN2 (0.33) | SMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL31163791 | 0.93 | SMN1; SMN2 (0.33) | SMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL31163776 | 0.93 | SMN1; SMN2 (0.33) | SMN1; SMN2KDM4E | |
| SCHEMBL31163795 | 0.89 | MAPT (0.33) | KDM4ETP53 | |
| SCHEMBL31163805 | 0.88 | GBA1 (0.31) | — | |
| SCHEMBL31163694 | 0.87 | GBA1 (0.39) | TP53 | |
| SCHEMBL31163682 | 0.87 | GBA1 (0.39) | TP53 | |
| SCHEMBL31163866 | 0.86 | KDM4E (0.34) | SMN1; SMN2KDM4ETP53 | |
| SCHEMBL31163882 | 0.81 | GBA1 (0.30) | — | |
| SCHEMBL31163920 | 0.81 | GBA2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024179491-A1 | GBA1 AND GCS DUAL MODULATOR | ONO PHARMACEUTICAL CO., LTD. (JP) | 2024-09-06 | — | — | WO | disclosed |