⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4602727 | 0.89 | — | — | |
| SCHEMBL2223857 | 0.89 | — | — | |
| SCHEMBL21114245 | 0.86 | — | — | |
| SCHEMBL21114338 | 0.86 | — | — | |
| SCHEMBL6593778 | 0.86 | — | — | |
| SCHEMBL3622632 | 0.86 | — | — | |
| SCHEMBL6588867 | 0.86 | — | — | |
| SCHEMBL21114315 | 0.86 | — | — | |
| SCHEMBL21114248 | 0.86 | — | — | |
| SCHEMBL3625962 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662849-B2 | Amidino compounds as cysteine protease inhibitors | VIROBAY, INC. (US) | 2010-02-16 | — | — | US | claimed |
| US-20070276019-A1 | Haloalkyl Containing Compounds as Cysteine Protease Inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2007-11-29 | — | — | US | claimed |
| EP-1761485-A1 | AMIDINO COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | Schering AG (DE) | 2007-03-14 | — | — | EP | claimed |
| JP-2006526657-A | — | — | 2006-11-24 | — | — | JP | claimed |
| US-20060264464-A1 | Amidino compounds as cysteine protease inhibitors | QUEST DIAGNOSTICS INVESTMENTS LLC | 2006-11-23 | — | — | US | claimed |
| EP-1664003-A1 | HALOALKYL CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2006-06-07 | — | — | EP | claimed |
| WO-2005028454-A1 | HALOALKYL CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-31 | — | — | WO | claimed |
| WO-2004108661-A1 | AMIDINO COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS (US) | 2004-12-16 | — | — | WO | claimed |
| US-6809108-B1 | SELECTIVE MUSCARINIC M3 RECEPTOR ANTAGONTS; REDUCED SIDE EFFECTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-10-26 | — | — | US | claimed |
| EP-1213281-B1 | NOVEL AMIDE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-02-18 | — | — | EP | claimed |
| EP-1213281-A1 | NOVEL AMIDE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-06-12 | — | — | EP | claimed |
| US-4754059-A | ANTISECRETORY AGENT WITH REDUCED DIARRHEA SIDE EFFECT | G. D. SEARLE & CO. (US) | 1988-06-28 | — | — | US | claimed |
| US-11981670-B2 | Alkyl chain modified imidazoquinoline TLR7/8 agonist compounds and uses thereof | DYNAVAX TECHNOLOGIES CORPORATION (US) | 2024-05-14 | — | — | US | disclosed |
| EP-4257198-A2 | ALKYL CHAIN MODIFIED IMIDAZOQUINOLINE DERIVATIVES AS TLR7/8 AGONISTS AND USES THEREOF | Dynavax Technologies Corporation (US) | 2023-10-11 | — | — | EP | disclosed |
| EP-3672969-B1 | ALKYL CHAIN MODIFIED IMIDAZOQUINOLINE DERIVATIVES AS TLR7/8 AGONISTS AND USES THEREOF | DYNAVAX TECH CORP (US) | 2023-07-05 | — | — | EP | disclosed |
| EP-4011875-A1 | TRIAZOLE N-LINKED CARBAMOYL CYCLOHEXYL ACIDS AS LPA ANTAGONISTS | Bristol-Myers Squibb Company (US) | 2022-06-15 | — | — | EP | disclosed |
| EP-1213281-A1 | NOVEL AMIDE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-06-12 | — | — | EP | disclosed |
| EP-1194407-A2 | N-CYCLOALKYL-3-ALKENYLBENZOYL-PYRAZOLE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2002-04-10 | — | — | EP | disclosed |
| WO-2001004096-A2 | N-CYCLOALKYL-3-ALKENYLBENZOYL-PYRAZOLE DERIVATIVES AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2001-01-18 | — | — | WO | disclosed |
| US-5502073-A | INSECTICIDES OR ANTHELMINTICS | THE WELLCOME FOUNDATION (GB) | 1996-03-26 | — | — | US | disclosed |