SCHEMBL31167701

SCHEMBL31167701

COC(=O)c1cnc(C)cc1-c1cc(C=O)nnc1OC

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ POLQ O75417 19/20 0.51
▸ GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31167718 0.90 POLQ (0.49) POLQGAA
SCHEMBL30017993 0.88 POLQ (0.62) POLQ
SCHEMBL24770879 0.88 POLQ (0.62) POLQ
SCHEMBL31214191 0.84 POLQ (0.52) POLQ
SCHEMBL24770099 0.84 POLQ (0.52) POLQ
SCHEMBL30018348 0.84 POLQ (0.52) POLQ
SCHEMBL24769282 0.82 POLQ (0.48) POLQ
SCHEMBL31167648 0.81 POLQ (0.49) POLQ
SCHEMBL31598622 0.77 POLQ (0.47) POLQ
SCHEMBL30905062 0.77 POLQ (0.47) POLQ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4688772-A1 BIARYL DERIVATIVES AND RELATED USES Moma Therapeutics, Inc. (US) 2026-02-11 — — EP disclosed
US-20260015360-A1 BIARYL DERIVATIVES AND RELATED USES MOMA THERAPEUTICS, INC. 2026-01-15 — — US disclosed
WO-2024211834-A1 BIARYL DERIVATIVES AND RELATED USES MOMA THERAPEUTICS, INC. (US) 2024-10-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015360-A1 BIARYL DERIVATIVES AND RELATED USES POLB, POLA1, POLN POLQ 15/4885GAA 382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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