Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 18/20 | 0.58 |
| ▸ | PDE4A | P27815 | 9/20 | 0.58 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15194245 | 1.00 | PDE4B (0.58) | PDE4BPDE4APDE4CPDE4DSMN1; SMN2 | |
| SCHEMBL15202855 | 1.00 | PDE4B (0.58) | PDE4BPDE4APDE4CPDE4DSMN1; SMN2 | |
| SCHEMBL15194423 | 1.00 | PDE4B (0.58) | PDE4BPDE4APDE4CPDE4DSMN1; SMN2 | |
| SCHEMBL31380927 | 0.90 | PDE4B (0.59) | PDE4BPDE4APDE4CPDE4DSMN1; SMN2 | |
| SCHEMBL15202689 | 0.88 | SMN1; SMN2 (0.51) | PDE4BPDE4APDE4CPDE4DSMN1; SMN2 | |
| SCHEMBL18920444 | 0.82 | PDE4B (0.55) | PDE4BPDE4APDE4CPDE4DSMN1; SMN2 | |
| SCHEMBL5552819 | 0.82 | PDE4B (0.63) | PDE4BPDE4APDE4CPDE4DHTR2B | |
| SCHEMBL19490721 | 0.82 | PDE4B (0.57) | PDE4BPDE4APDE4CPDE4DSMN1; SMN2 | |
| SCHEMBL18281288 | 0.81 | PDE4B (0.55) | PDE4BPDE4APDE4CPDE4DSMN1; SMN2 | |
| SCHEMBL18281290 | 0.81 | PDE4B (0.55) | PDE4BPDE4APDE4CPDE4DSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118834155-A | Preparation method of apremilast | 江苏知原药业股份有限公司 | 2024-10-25 | — | — | CN | disclosed |