Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1818004 | 1.00 | GBA1 (0.36) | GBA1HSD17B10ALDH1A1KDM4EATM | |
| SCHEMBL15001188 | 0.82 | GBA1 (0.35) | GBA1ALDH1A1KDM4EADRA2AADRA2B | |
| SCHEMBL15001209 | 0.82 | GBA1 (0.35) | GBA1ALDH1A1KDM4EADRA2AADRA2B | |
| SCHEMBL15001190 | 0.82 | GBA1 (0.35) | GBA1ALDH1A1KDM4EADRA2AADRA2B | |
| SCHEMBL210731 | 0.80 | GBA1 (0.35) | GBA1ALDH1A1KDM4EATMRAB9A | |
| SCHEMBL1818566 | 0.79 | GBA1 (0.41) | GBA1ALDH1A1KDM4EATMRAB9A | |
| SCHEMBL19062001 | 0.79 | GBA1 (0.33) | GBA1ALDH1A1KDM4EADRA2AADRA2B | |
| SCHEMBL29926723 | 0.79 | GBA1 (0.41) | GBA1ALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL681100 | 0.79 | GBA1 (0.41) | GBA1ALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL3509480 | 0.78 | GBA1 (0.33) | GBA1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118748993-A | Indazole compounds and medicaments | 日本新药株式会社 | 2024-10-08 | — | — | CN | disclosed |