SCHEMBL31169600

SCHEMBL31169600

Cc1cc(-c2ccnc(Nc3ccc(N4CCN(CC5CCN(C(=O)c6cccc(N7CCC(=O)NC7=O)c6)CC5)CC4)cc3)n2)ccc1CNC(=O)N1CC(OC(C)C)C1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ BTK Q06187 15/20 0.53
▸ JAK2 O60674 3/20 0.53
▸ CD69 Q07108 2/20 0.53
▸ CYP3A4 P08684 1/20 0.53
▸ HRH2 P25021 1/20 0.53
▸ CDK7 P50613 1/20 0.53
▸ AAK1 Q2M2I8 1/20 0.53
▸ MAP3K19 Q56UN5 1/20 0.53
▸ CDKL2 Q92772 1/20 0.53
▸ RIOK1 Q9BRS2 1/20 0.53
▸ RIOK2 Q9BVS4 1/20 0.53
▸ BMP2K Q9NSY1 1/20 0.53
▸ SYK P43405 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25173935 1.00 BTK (0.53) BTKJAK2CD69CYP3A4HRH2
SCHEMBL25170622 0.94 BTK (0.56) BTKJAK2CD69CYP3A4HRH2
SCHEMBL31169602 0.94 BTK (0.56) BTKJAK2CD69CYP3A4HRH2
SCHEMBL31169613 0.93 BTK (0.59) BTKJAK2CD69CYP3A4HRH2
SCHEMBL25170795 0.93 BTK (0.59) BTKJAK2CD69CYP3A4HRH2
SCHEMBL25176367 0.91 BTK (0.51) BTKJAK2CD69CYP3A4HRH2
SCHEMBL30434288 0.91 BTK (0.51) BTKJAK2CD69CYP3A4HRH2
SCHEMBL25176341 0.90 BTK (0.55) BTKJAK2CD69CYP3A4HRH2
SCHEMBL30434222 0.90 BTK (0.55) BTKJAK2CD69CYP3A4HRH2
SCHEMBL25167760 0.90 BTK (0.56) BTKJAK2CD69CYP3A4HRH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250041429-A1 COMPOUND HAVING BTK PROTEIN DEGRADATION ACTIVITY, AND MEDICAL USES THEREOF UBIX THERAPEUTICS, INC. (KR) 2025-02-06 — — US disclosed
EP-4428130-A1 COMPOUND HAVING BTK PROTEIN DEGRADATION ACTIVITY, AND MEDICAL USES THEREOF Ubix Therapeutics, Inc. (KR) 2024-09-11 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250041429-A1 COMPOUND HAVING BTK PROTEIN DEGRADATION ACTIVITY, AND MEDICAL USES THEREOF BTK, LYN, SYK BTK 1/4885JAK2 7/4885CD69 2351/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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