SCHEMBL31169607

SCHEMBL31169607

CC(C)(C)OC(=O)N1CCN(c2ccc(OC3CCC(=O)NC3=O)cn2)CC1

nearest known ligand 0.68

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 14/20 0.68
▸ CRBN Q96SW2 14/20 0.68
▸ GPR119 Q8TDV5 3/20 0.51
▸ MAP4K4 O95819 1/20 0.44
▸ CKS1B P61024 1/20 0.43
▸ SKP1 P63208 1/20 0.43
▸ SKP2 Q13309 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25176698 1.00 DDB1 (0.68) DDB1CRBNGPR119MAP4K4CKS1B
SCHEMBL27036800 0.87 DDB1 (0.58) DDB1CRBNGPR119
SCHEMBL20595415 0.85 DDB1 (0.74) DDB1CRBNGPR119
SCHEMBL21903077 0.85 DDB1 (0.74) DDB1CRBNGPR119
SCHEMBL29744797 0.85 DDB1 (0.74) DDB1CRBNGPR119
SCHEMBL24125934 0.85 DDB1 (0.58) DDB1CRBNGPR119
SCHEMBL25074522 0.83 CRBN (0.70) DDB1CRBNGPR119MAP4K4CKS1B
SCHEMBL24881041 0.83 CRBN (0.70) DDB1CRBNGPR119MAP4K4CKS1B
SCHEMBL29977355 0.83 CRBN (0.70) DDB1CRBNGPR119MAP4K4CKS1B
SCHEMBL29208509 0.83 CRBN (0.70) DDB1CRBNGPR119MAP4K4CKS1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250041429-A1 COMPOUND HAVING BTK PROTEIN DEGRADATION ACTIVITY, AND MEDICAL USES THEREOF UBIX THERAPEUTICS, INC. (KR) 2025-02-06 — — US disclosed
EP-4428130-A1 COMPOUND HAVING BTK PROTEIN DEGRADATION ACTIVITY, AND MEDICAL USES THEREOF Ubix Therapeutics, Inc. (KR) 2024-09-11 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250041429-A1 COMPOUND HAVING BTK PROTEIN DEGRADATION ACTIVITY, AND MEDICAL USES THEREOF BTK, LYN, SYK DDB1 1245/4885CRBN 324/4885GPR119 3705/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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