Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.74 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24717210 | 0.92 | KRAS (0.62) | KRAS | |
| SCHEMBL31542459 | 0.90 | KRAS (0.80) | KRASMAPK3MAPK1 | |
| SCHEMBL25918465 | 0.90 | KRAS (0.80) | KRASMAPK3MAPK1 | |
| SCHEMBL30623536 | 0.89 | KRAS (0.79) | KRASMAPK3MAPK1 | |
| SCHEMBL25917865 | 0.89 | KRAS (0.79) | KRASMAPK3MAPK1 | |
| SCHEMBL27033778 | 0.89 | KRAS (0.88) | KRASMAPK3MAPK1 | |
| SCHEMBL25921391 | 0.89 | KRAS (0.88) | KRASMAPK3MAPK1 | |
| SCHEMBL31578616 | 0.88 | KRAS (0.87) | KRASMAPK3MAPK1 | |
| SCHEMBL25406046 | 0.88 | KRAS (0.87) | KRASMAPK3MAPK1 | |
| SCHEMBL30548069 | 0.88 | KRAS (0.87) | KRASMAPK3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4712961-A2 | KRAS G12S AND G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| WO-2024238633-A2 | KRAS G12S AND G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2024-11-21 | — | — | WO | disclosed |