Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25258920 | 1.00 | EPHX2 (0.40) | EPHX2USP2SMN1; SMN2EPHX1NR1H2 | |
| SCHEMBL30523528 | 1.00 | EPHX2 (0.40) | EPHX2USP2SMN1; SMN2EPHX1NR1H2 | |
| SCHEMBL30523509 | 1.00 | EPHX2 (0.40) | EPHX2USP2SMN1; SMN2EPHX1NR1H2 | |
| SCHEMBL16984292 | 0.83 | USP2 (0.44) | EPHX2USP2SMN1; SMN2EPHX1NR1H2 | |
| SCHEMBL24716561 | 0.75 | HPGD (0.42) | EPHX2USP2SMN1; SMN2EPHX1NR1H2 | |
| SCHEMBL18149873 | 0.75 | USP2 (0.45) | EPHX2USP2SMN1; SMN2EPHX1NR1H2 | |
| SCHEMBL20973866 | 0.75 | CHRM2 (0.42) | EPHX2USP2SMN1; SMN2EPHX1NR1H2 | |
| SCHEMBL31057506 | 0.75 | CHRM2 (0.42) | EPHX2USP2SMN1; SMN2EPHX1NR1H2 | |
| SCHEMBL6114687 | 0.75 | CHRM2 (0.45) | EPHX2USP2SMN1; SMN2EPHX1NR1H2 | |
| SCHEMBL16122957 | 0.75 | USP2 (0.43) | EPHX2USP2SMN1; SMN2EPHX1NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4446312-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING NRF2 ACTIVATION EFFECT | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-10-16 | — | — | EP | disclosed |