SCHEMBL3117255

SCHEMBL3117255

CCCC(C)CC(COS(=O)(=O)c1ccc(C)cc1)CC(=O)OC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
ALDH1A1 P00352 3/20 0.33
STAT3 P40763 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
NR1D1 P20393 1/20 0.33
HTT P42858 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MMP13 P45452 1/20 0.33
CTDSP1 Q9GZU7 1/20 0.32
SIRT5 Q9NXA8 1/20 0.32
TSHR P16473 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
MDM2 Q00987 1/20 0.32
PSEN1 P49768 3/20 0.31
PSEN2 P49810 3/20 0.31
APH1B Q8WW43 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3833448 1.00 CA12 (0.36) CA12CA2CA9ALDH1A1STAT3
SCHEMBL3116629 1.00 CA12 (0.36) CA12CA2CA9ALDH1A1STAT3
SCHEMBL7213256 1.00 CA12 (0.36) CA12CA2CA9ALDH1A1STAT3
SCHEMBL3122917 0.94 PLA2G2C (0.34) CA12CA2CA9ALDH1A1STAT3
SCHEMBL3123597 0.93 PLA2G2C (0.36) CA12CA2CA9ALDH1A1STAT3
SCHEMBL3118259 0.93 PLA2G2C (0.36) CA12CA2CA9ALDH1A1STAT3
SCHEMBL27486951 0.93 PLA2G2C (0.36) CA12CA2CA9ALDH1A1STAT3
SCHEMBL4374409 0.91 KMT2A (0.35) CA2ALDH1A1STAT3MEN1KMT2A
SCHEMBL3831947 0.91 KMT2A (0.35) CA2ALDH1A1STAT3MEN1KMT2A
SCHEMBL3116664 0.91 KMT2A (0.35) CA2ALDH1A1STAT3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2172197-A1 Octanoic acid derivative to treat fibromyalgia and other pains Warner-Lambert Company LLC (US) 2010-04-07 EP disclosed