SCHEMBL31173111

SCHEMBL31173111

Cc1ccc(N)cc1NC(=O)c1ccc(CN2CCN(C)CC2)c(C(F)(F)F)c1

nearest known ligand 0.71

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ BRAF P15056 11/20 0.71
▸ EGFR P00533 9/20 0.71
▸ KIT P10721 8/20 0.68
▸ CSF1R P07333 7/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3561769 0.85 KIT (0.76) BRAFEGFRKITCSF1R
SCHEMBL3557025 0.84 BRAF (0.74) BRAFEGFRKITCSF1R
SCHEMBL22024687 0.84 BRAF (0.76) BRAFEGFRKITCSF1R
SCHEMBL17537391 0.83 KIT (0.80) BRAFEGFRKITCSF1R
SCHEMBL31172995 0.83 BRAF (0.72) BRAFEGFRKITCSF1R
SCHEMBL31620739 0.83 BRAF (0.86) BRAFEGFRKITCSF1R
SCHEMBL4254627 0.83 KIT (0.79) BRAFEGFRKIT
SCHEMBL588917 0.83 KIT (0.93) BRAFEGFRKITCSF1R
SCHEMBL22024526 0.82 BRAF (0.73) BRAFEGFRKITCSF1R
SCHEMBL22024682 0.82 BRAF (0.82) BRAFEGFRKITCSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4676600-A1 PROTEIN KINASE INHIBITORS AND USES THEREOF Deliver Therapeutics, Inc. (US) 2026-01-14 — — EP disclosed
WO-2024186579-A1 PROTEIN KINASE INHIBITORS AND USES THEREOF DELIVER THERAPEUTICS, INC. (US) 2024-09-12 — — WO disclosed
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