Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.50 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.44 |
| ▸ | KLK1 | P06870 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | VNN1 | O95497 | 3/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | GLMN | Q92990 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.42 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25370305 | 1.00 | ERCC1 (0.50) | ERCC1ERCC4SMN1; SMN2CNR1NAMPT | |
| SCHEMBL25369701 | 0.89 | ERCC1 (0.49) | ERCC1ERCC4SMN1; SMN2CNR1NAMPT | |
| SCHEMBL31173726 | 0.89 | ERCC1 (0.49) | ERCC1ERCC4SMN1; SMN2CNR1NAMPT | |
| SCHEMBL25372468 | 0.85 | ERCC1 (0.46) | ERCC1ERCC4SMN1; SMN2CNR1NAMPT | |
| SCHEMBL30580154 | 0.85 | ERCC1 (0.46) | ERCC1ERCC4SMN1; SMN2CNR1NAMPT | |
| SCHEMBL25369595 | 0.85 | ERCC1 (0.46) | ERCC1ERCC4SMN1; SMN2CNR1NAMPT | |
| SCHEMBL30580137 | 0.85 | ERCC1 (0.46) | ERCC1ERCC4SMN1; SMN2CNR1NAMPT | |
| SCHEMBL26051521 | 0.82 | EPHX2 (0.46) | ERCC1ERCC4SMN1; SMN2CNR1NAMPT | |
| SCHEMBL13853501 | 0.81 | ERCC1 (0.56) | ERCC1ERCC4SMN1; SMN2CNR1NAMPT | |
| SCHEMBL25369559 | 0.79 | CYP3A4 (0.54) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250002452-A1 | BICYCLOPENTANE DERIVATIVES | ANGELINI PHARMA S.P.A. (IT) | 2025-01-02 | — | — | US | claimed |
| US-20250002452-A1 | BICYCLOPENTANE DERIVATIVES | ANGELINI PHARMA S.P.A. (IT) | 2025-01-02 | — | — | US | disclosed |
| CN-118829626-A | Novel dicyclopentane derivatives | 伊卡根有限责任公司 | 2024-10-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250002452-A1 | BICYCLOPENTANE DERIVATIVES | BICRA, C1R, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | ERCC1 865/4885ERCC4 932/4885SMN1; SMN2 3372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.