Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 3/20 | 0.39 |
| ▸ | FLT3 | P36888 | 3/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25093965 | 1.00 | PARP1 (0.48) | PARP1EPHX2RAF1BRAFUSP30 | |
| SCHEMBL30888908 | 0.91 | USP30 (0.51) | EPHX2RAF1BRAFUSP30GPR119 | |
| SCHEMBL25286886 | 0.91 | USP30 (0.51) | EPHX2RAF1BRAFUSP30GPR119 | |
| SCHEMBL30896212 | 0.91 | USP30 (0.51) | EPHX2RAF1BRAFUSP30GPR119 | |
| SCHEMBL25243822 | 0.91 | USP30 (0.51) | EPHX2RAF1BRAFUSP30GPR119 | |
| SCHEMBL30902535 | 0.91 | USP30 (0.51) | EPHX2RAF1BRAFUSP30GPR119 | |
| SCHEMBL31362194 | 0.91 | USP30 (0.51) | EPHX2RAF1BRAFUSP30GPR119 | |
| SCHEMBL12670379 | 0.89 | MEN1 (0.43) | PARP1EPHX2RAF1BRAFUSP30 | |
| SCHEMBL25193220 | 0.88 | USP30 (0.54) | EPHX2RAF1BRAFUSP30GPR119 | |
| SCHEMBL29220834 | 0.88 | PIK3CD (0.47) | PARP1EPHX2USP30MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250289814-A1 | COMPOUNDS AS PARP1 INHIBITIORS | NINGBO NEWBAY TECH DEVELOPMENT CO LTD (CN) | 2025-09-18 | — | — | US | disclosed |
| WO-2025073583-A1 | PARP1 INHIBITOR COMPOUNDS | Duke Street Bio Limited (GB) | 2025-04-10 | — | — | WO | disclosed |
| WO-2024227033-A1 | HETEROCYCLIC COMPOUNDS AS PARP1 INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2024-10-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250289814-A1 | COMPOUNDS AS PARP1 INHIBITIORS | PARP1, PARP11, PARP12 | PARP1 1/4885EPHX2 4662/4885RAF1 2057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.