Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 9/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 2/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11301251 | 1.00 | ERN1 (0.53) | ERN1TDP1ALDH1A1MEN1NPC1 | |
| SCHEMBL2918452 | 0.92 | ERN1 (0.50) | ERN1TDP1ALDH1A1MEN1NPC1 | |
| SCHEMBL3227837 | 0.83 | ERN1 (0.50) | ERN1TDP1ALDH1A1MEN1NPC1 | |
| SCHEMBL31442964 | 0.82 | ERN1 (0.61) | ERN1TDP1ALDH1A1MEN1NPC1 | |
| SCHEMBL17807916 | 0.82 | ERN1 (0.56) | ERN1TYRTRIM24TRIM33 | |
| SCHEMBL1922524 | 0.82 | ERN1 (0.61) | ERN1TDP1ALDH1A1MEN1NPC1 | |
| SCHEMBL25240603 | 0.80 | ERN1 (0.59) | ERN1TDP1ALDH1A1MEN1NPC1 | |
| SCHEMBL1860423 | 0.80 | ERN1 (0.54) | ERN1TYRTRIM24TRIM33 | |
| SCHEMBL30064066 | 0.80 | ERN1 (0.54) | ERN1TYRTRIM24TRIM33 | |
| SCHEMBL1922020 | 0.77 | ERN1 (0.55) | ERN1TDP1ALDH1A1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220917-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2024-10-24 | — | — | WO | disclosed |