Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH2 | P05091 | 6/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.40 |
| ▸ | HPGD | P15428 | 8/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312735 | 0.92 | ALDH2 (0.43) | ALDH2MAOBKDM4EHPGDHSD17B10 | |
| SCHEMBL10215504 | 0.86 | MAOB (0.52) | ALDH2MAOBKDM4EHPGDHSD17B10 | |
| SCHEMBL312060 | 0.81 | HPGD (0.44) | MAOBKDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL312824 | 0.81 | HPGD (0.40) | ALDH2MAOBKDM4EHPGDHSD17B10 | |
| SCHEMBL312118 | 0.81 | MAOB (0.43) | ALDH2MAOBKDM4EHPGDHSD17B10 | |
| SCHEMBL311364 | 0.77 | HPGD (0.44) | MAOBKDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL311578 | 0.72 | HPGD (0.45) | MAOBKDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL311616 | 0.71 | KDM4E (0.52) | MAOBKDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL313350 | 0.71 | KDM4E (0.44) | MAOBKDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL311741 | 0.71 | KDM4E (0.40) | MAOBKDM4EHPGDHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093273-B2 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-01-10 | — | — | US | disclosed |
| EP-2332527-A2 | Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2011-06-15 | — | — | EP | disclosed |