Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | TP53 | P04637 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | PNLIP | P16233 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31185167 | 1.00 | GLA (0.67) | GLAALDH1A1KMT2ATP53LMNA | |
| SCHEMBL31185236 | 0.84 | HTT (0.68) | ALDH1A1KMT2ATP53LMNAMEN1 | |
| SCHEMBL29279417 | 0.84 | HTT (0.68) | ALDH1A1KMT2ATP53LMNAMEN1 | |
| SCHEMBL2091571 | 0.81 | GLA (0.71) | GLAALDH1A1KMT2ATP53LMNA | |
| SCHEMBL6783366 | 0.81 | GLA (0.71) | GLAALDH1A1KMT2ATP53LMNA | |
| SCHEMBL2091569 | 0.81 | GLA (0.71) | GLAALDH1A1KMT2ATP53LMNA | |
| SCHEMBL24047280 | 0.80 | GLA (0.69) | GLAALDH1A1KMT2ATP53LMNA | |
| SCHEMBL2095026 | 0.80 | GLA (0.69) | GLAALDH1A1KMT2ATP53LMNA | |
| SCHEMBL5188506 | 0.80 | GLA (1.00) | GLAALDH1A1KMT2ATP53LMNA | |
| SCHEMBL4112840 | 0.79 | GLA (0.63) | GLAALDH1A1KMT2ATP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685473-B | 5-Alkyl-2-pyrazole-oxazolidine-4-ketone derivative and application thereof | 杭州百新生物医药科技有限公司 | 2024-10-29 | — | — | CN | disclosed |